A PDE5 blocker called sildenafil citrate, which is a salt, is being used to treat erectile dysfunction in males. This treatment is intended to cure the condition. This treatment is available in a number of different formulations, including liquid, pill, and intravenous administration. Patients, however, should never administer intravenous medication to themselves unless they are under the supervision of a trained medical expert. Both the unbranded and the branded versions of this medication are available for purchase to customers. Sildenafil is sold under a variety of brand names, the most well-known of which being Viagra and Revatio.
The implementation of sildenafil citrate
By using several drugs, such as Cenforce, Fildena, Malegra and Kamagra, amongst others, they are able to experience the effects of PDE5 inhibitors. This active ingredient provides the strength that men need to keep their erections firm for an extended period of time. However, in order for patients to benefit from this treatment, they must be sexually aroused. After taking this prescription, the pair will be able to engage in sexual activity without interruption for up to four hours.
How exactly does sildenafil citrate operate after it’s been absorbe into the body?
Erection difficulties might arise when the penis does not get a sufficient flow of blood. It is difficult to penetrate because the penis secretes an enzyme called PDE-5. This enzyme prevents the storage of cyclic guanosine monophosphate, which impedes blood flow in the penis and makes penetration more difficult.
On the other hand, sildenafil citrate inhibits PDE5, which results in an increase in cGMP levels in the corpus cavernosum. As a consequence of this, the chemical messenger known as nitric oxide is produce, and its effects include the relaxation of the penile muscles. In the end, this causes an erection that is really strong and lasts for a long time.
How should sildenafil citrate be taken?
Patients who choose to take this medication are advise to abstain from engaging in activities such as consuming an excessive amount of alcohol or smoking. You may consume low-fat meals if you wish to take this pill with food so that you won’t have an empty stomach after taking it. To have the greatest possible outcome, however, it is recommend that this medication be take on an empty stomach.
You are require to take this tablet together with an adequate amount of water, and you must take this pill at least thirty to sixty minutes before engaging in sexual activity with your partner. Patients shouldn’t consume grapefruit juice since it contains CYP3A4, which prevents this drug from being metabolism in the liver by the CYP3A4 inhibitor.
The recommended dose of sildenafil citrate
This treatment is offer in a variety of dosage levels, ranging from 50 mg to 100 mg of sildenafil. Patients do not have any notion regarding dose modification. In order to accomplish this goal, medical aid is require in significant quantity. Patients are only allow to take one tablet at a time during a period of 24 hours. Even for them, it is imperative that they keep taking this drug until the physician instructs them otherwise.
If you ever get the feeling that you have taken a higher dose than you should have, you should seek medical attention as soon as possible in order to cure the adverse consequences, which may include difficulty breathing, itching, infertility, tiredness, and many other symptoms.
Patients are instruct to take this medication at a certain time every day. But in the event that you are ever unable to do so, seize the opportunity whenever it presents itself. However, you should make it a priority to ensure that you will take a missed dosage while there is still sufficient time before the next scheduled dose. In such case, you should stop taking the dosage that didn’t work and instead take just the new dose. Never take a duplicate dosage to make up for a missed one while taking medication.
Patients who use this medication may have adverse effects ranging from mild to severe after doing so. Patients do not need to make an appointment with a medical professional in order to address common or moderate side effects such as muscular discomfort, stomach ache, dizziness, nosebleeds, or diarrhoea. However, in order to avoid significant side effects including priapism, painful urination, swelling of the face and neck, and infertility, medical intervention is absolutely necessary and strongly recommended.
Who should not use the Sildenafil citrate medication?
Avoid bringing infants, children under the age of 18, ladies, or pets into the same room as this medication.
Patients who suffer from co-morbidities such as diabetes and cardiovascular disorders such as irregular heartbeat and stroke should not take this drug, since it is likely to be lethal for them if they do so. In addition to these things, those who have conditions such as liver disease, renal illness, thyroid disease, or hypertension should exercise extreme caution while taking it.
Patients are require to seek emergency medical attention if they continue to suffer from a painful erection after a period of four hours. In the event that this does not occur, the tissue of the penis will be injure, and patients will have irreversible impotence.
This drug should not be use by patients who have a penis that is angular or malformed, fibrosis, or blood cell abnormalities such as sickle cell anaemia or myeloma. They have a greater propensity to engage in priapism.
Patients who have a serious bleeding disease, such as an active ulcer or a peptic ulcer, are strongly discourage from using this medication.
Interactions between drugs
Hepatitis C vaccination Amlodipine Alpha-blockers such as Doxazosin and Tamsulosin Hepatitis C vaccine
Where should I store it?
It is important to remember to keep this medication in a cool, dry, and dark area. After you have removed the item from its original packaging, you must place it in an airtight container and store it at a temperature of less than 30 degrees Celsius.
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